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Data science continues to evolve to support increasing demands for predictive insights and dynamic systems. The innovation in this field is welcomed and is changing all industry sectors, including medtech manufacturing. Forward-thinking companies are mindful of the need to develop capabilities to compete in a digital economy. That doesn’t mean it is always clear how to adopt these innovations—or easy, for that matter. It is essential for organizations to outline a digital adoption roadmap to achieve their digitization goals and maintain future relevance. This article will provide a model for digital maturity that manufacturers can compare themselves against, as well as outline some of the current trends with digitization in medical device manufacturing. It will include some practical strategies to increase digital capabilities and some real use cases to illustrate how medtech manufacturers can realize tangible benefits from digitization, specifically through integration with innovative software and manufacturing tools.